Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 615.3:547.854.4

Synthesis of novel diarylacetamide derivatives of 2-thiouracil as potential antiviral agents

K. N. Lysenko, A. N. Geisman, A. A. Ozerov, M. S. Novikov

Волгоградский государственный медицинский университет, кафедра фармацевтической и токсикологической химии; Волгоградский медицинский научный центр, лаборатория медицинской химии


Novel 2-S-substituted 2-sulfanylpyrimidinone analogs were obtained via condensation of N-diarylsubstituted 2-chloro- acetanilides with 2-thiouracil derivatives. Physico-chemical and spectral properties of the synthesized compounds were studied. These compounds are considered as inhibitors of viral reproduction.


synthesis, 2-thiouracil, antiviral agents