Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: УДК 616.091.8:616.-092.9:57.042

A. V. Smirnov, M. V. Schmidt, M. R. Ekova, D. S. Mednikov, I. N. Tyurenkov, D. D. Borodin, A. S. Rustanova

A. V. Smirnov, M. V. Schmidt, M. R. Ekova, D. S. Mednikov, I. N. Tyurenkov, D. D. Borodin, A. S. Rustanova

Волгоградский государственный медицинский университет, кафедра патологической анатомии, кафедра фармакологии и биофармации ФУВ, лаборатория морфологии, иммуногистохимии и канцерогенеза ГБУ «Волгоградский медицинский научный центр»

Abstract

The daily exposure of rats to 30 minutes’ sessions of combined stress induced by removable multi-modal stressors (noise, vibration, pulsating bright light ) using the stochastic scheme coupled with restricted mobility and a rise in the chamber temperature from 20–22 °С to 25–27 °С for seven days made it possible to reveal the signs of neuronal damage in hippocampal dentate gyrus of adult rats (12 months) as well as circulatory disturbances in the microvasculature.

Keywords

dentate gyrus, hippocampus, neuron, rat, stress.

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