UDK: 616-091.8

Endotheliopathy of lung vessels in the dynamics of development of COVID-19

Sergei S. Todorov, Sergei S. Todorov jr. , Andrey S. Kazmin

Ростовский государственный медицинский университет, Ростов-на-Дону, Россия

Abstract

The review of the literature is devoted to the analysis of morphological changes in the vessels of the lungs with COVID-19, taking into account the dynamics of the development of the pathological process. Particular attention is paid to the role of endotheliocytes in the walls of pulmonary vessels – the main target for COVID-19 with the development of progressive endotheliopathy with the development of increased vascular permeability, fibrinoid swelling and necrosis, thrombosis, which are most pronounced by the end of the 3rd week of the disease

Keywords

COVID-19, endotheliopathy, dynamics of disease development, vascular microthrombosis

Contacts

sertodorov@gmail.com, https://orcid.org/0000-0001-8476-5606, SPIN – 4404-3176; todorov-00@inbox.ru, https://orcid.org/0000-0003-4787-403, SPIN – 3799-9516; kazmin_as@mail.ru, https://orcid.org/0000-0003-0934-3416, SPIN – 5944-3655