UDK: 616-005.4:611.813.14:616-092.9

Morphometric analysis of the pyramidal layer of the hippocampus of rats in the carotid arteries stenosis experimental modeling

Волгоградский государственный медицинский университет, кафедра патологической анатомии, кафедра фармакологии и фармации Института НМФО, Россия; Волгоградский медицинский научный центр, лаборатория патоморфологии, Россия

Abstract

The issue demonstrates the results of software morphometric analysis of the pyramidal layer of the hippocampus of rats with simulated stenosis of the carotid arteries. We have identified most pronounced changes in CA1 of the pyramidal layer of the hippocampus, where the number of neurons with signs of damage in both the hippocampus of the right and left hemispheres significantly increased. In addition, in CA1 of the pyramidal layer of the hippocampus of the left hemisphere, a significant decrease in the specific density of pyramidal neurons perikarya was revealed.

Keywords

hippocampus, rat, carotid stenosis

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