Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 616-091.8

Algorithm of computer morphometry in the diagnosis of pathological changes in rat hippocampal neurons experimental modeling of chronic alcohol intoxication

A. V. Smirnov, A. A. Zamlelov, M. V. Schmidt, D. Yu. Gurov

Волгоградский государственный медицинский университет, Россия, кафедра патологической анатомии; Волгоградский медицинский научный центр, Россия

Abstract

The study presents the developed algorithm of computer morphometry using the Image-Pro 4.5 software (Media Cybernetics, Inc., USA). The use of the Image-Pro 4.5 program in the morphological diagnosis of pathological changes in rat hippocampal neurons is demonstrated on the example of long-term forced chronic alcoholism. The obtained morphometric data serve as an objective assessment of absolute parameters of rat hippocampal neurons.

Keywords

computer morphometry, rat, hippocampus, alcohol intoxication

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