Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 616.45-001.1/.3-092.4

Indicators of group stress resistance in intact rats under the influence of a physiological stressor

L. N. Rogova, V. N. Povetkina, N. V. Shesternina, K. Y. Tikhaeva, T. V. Zamecnik, I. A. Fastova, V. A. Staravoitov, , Y. S. Dyachkova, G. V. Pankova

Волгоградский государственный медицинский университет, Россия, кафедра патофизиологии, клинической патофизиологии


In experiments on laboratory Wistar rats under anesthesia, indicators of group stress resistance were determined at the level of changes in animal behavior, humoral mechanisms, cellular and biochemical criteria under the influence of a physiological stressor (putting in a brightly lit chamber). Stress-resistant rats are characterized by high motor activity, low level of magnesium in red blood cells and blood plasma, associated with a large number of eNOS-positive cells against a background of minimal expression intensity in the stomach mucosa.


stress resistance, «open field» test, magnesium, endothelial nitric oxide synthase