Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 57.083.34

Role of cylin-dependent kinases 2,4,6 in the process of repair of insulocytes of the islandsof langerhans of the pancreatic gland

G. L. Snigur, S. S. Surin, D. A. Kavalerova

ФГБОУ ВО «Волгоградский государственный медицинский университет» МЗ РФ, кафедра биологии; ГБУ Волгоградский медицинский научный центр, лаборатория патоморфологии

Abstract

Cyclin-dependent kinases (CDKs) are a family of protein serine / threonine kinases whose activity depends on interaction with a non-catalytic regulatory subunit called cyclin. CDKs play an important role in cell cycle mechanisms respon- sible for coordinating cell growth, DNA replication, and mitosis which makes them necessary for proliferation [22]. This article reviews current information on the role of cyclin-dependent kinases in the repair of b-cells pancreatic islet of langerhans.

Keywords

cyclin-dependent kinases, proliferation, insulocytes

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