Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 615.214.32:616.895.4

Neurochemical of the mechanism of action of the adenine derivative

N. A. Mohammad Anim, T. M. Avilova

Волгоградский государственный медицинский университет, кафедра биологии

Abstract

The neurochemical mechanisms of the antidepressant action of the adenine derivative VMA-99-82 was studied using the method of high-yield liquid chromatography with electrochemical detection. Antidepressant action of adenine deriva- tive is possible caused of promoting effect on the noradrenergic and serotonergic systems of brain.

Keywords

antidepressant actions, adenine derivatives, neurochemical mechanisms, monoamines, rats

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