Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 58.087; 576.31

Anatomo-Morphological investigation of fruits Psoralea Corylifolia L. (Fabaceae)

A. V. Yanitskaya, M. A. Yarkovoy, E. V. Malaeva, I. V. Zemlyanskaya, O. G. Strusovskaya

Волгоградский государственный медицинский университет; Волгоградский медицинский научный центр; Волгоградский региональный ботанический сад; Волгоградский государственный социально-педагогический университет

Abstract

Phototherapy is a priority method of treatment and rehabilitation of patients with psoriasis, a pathology that has acquired social significance now. PUFA-therapy is a type of phototherapy that includes photosensitizers. The only photosensitizer of russian manufacture, "Ammifurin", was obtained on the basis of a large Ammi fruits extract. However, psoralen is considered to be the most effective and less toxic photosensitizer of this class of compounds. The resumption of production of the highly effective “Psoralen” drug available for the general population and possible for use in childhood is possible owing to usage of the biotechnological method for furocoumarin derivatives from callus tissue of the producing plant seeds seedlings production. The aim of the work was to identify fruits, presumably P. corylifolia, for their further use in the furocoumarin derivatives preparation with the biotechnological method.

Keywords

psoriasis, ammifurine, psoralene, fruits of Psoralea Corylifolia L

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