UDK: 615.272.4

Analysis of the efficacy and safety of statin therapy in extremely high-risk polymorbid patients cardiovascular risk

N. V. Izmozherova, A. A. Popov, V. M. Bakhtin

Уральский государственный медицинский университет, кафедра фармакологии и клинической фармакологии, кафедра госпитальной терапии и скорой медицинской помощи

Abstract

A cross-sectional current practice evaluation of statins treatment efficacy and safety has been performed in a sampling of 131 very-high cardiovascular risk outpatients. Polymorbidity has been found to be a characteristic feature of the sampling patients. In the higher polimorbidity patients statins were prescribed less frequently but in higher dosage than in moderately polimorbid ones. Target serum lipids levels were not achieved in most cases. The presence of concomitant conditions was not associated with statins adverse effects frequency increase.

Keywords

statins, pharmacotherapy, cardiovascular risk, safety, efficacy, polymorbidity, comorbidity

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