Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 615.281.9:615.454.1:582.675.3:616.31

Determination of antibacterial activity of the barbaris root extract in the dental gel form

A. G. Strusovskaya, S. V. Poroyskiy, O. G. Strusovskaya

Волгоградский государственный медицинский университет; ГБУ «Волгоградский медицинский научный центр», Волгоград

Abstract

Medications derived from herbal raw materials occupy an important place in modern medicine. From the vast group of biologically active substances of plant origin, protoberberin alkaloids, the main representative of which is berberine, stand out. It is known that berberine has a broad spectrum of biological activity, including antibacterial properties against periodontopathogenic bacteria, specifically inhibiting the growth of Porphyromonas gingivalis. Nowadays, periodontitis is a socially significant pathology, affecting all segments of the population. It has the possibility of development since even childhood. Antibiotic drugs used in the periodontitis treatment can lead to the emergence of microorganisms resistance. That is why it is important to create an effective dental form based on data from the study of antimicrobial activity of medicinal plant materials extracts.

Keywords

antimicrobial activity, berberis, periodontitis, gel

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