UDK: 617.52-089:616.716.4-002.4

Experimental modeling of osteonecrosis of the mandible

A. A. Nesterov, G. L. Snigur, YU. V. Yefimov, D. V. Mikhal chenko, S. S. Surin

Кафедра стоматологии и челюстно-лицевой хирургии с курсом последипломного образования АГМУ; кафедра биологии; кафедра хирургической стоматологии и челюстно-лицевой хирургии; кафедра пропедевтики стоматологических заболеваний ВолгГМУ

Abstract

A comparative analysis of histopathological changes in the experimental modeling of osteonecrosis of the mandible in outbred rats on the background of the administration of zoledronic acid, red phosphorus and phosphorus iodide (PI3) was performed. The optimal terms of the experiment on modeling bisphosphonate and desomorphine necrosis were determined.

Keywords

bisphosphonates, osteonecrosis, desomorphine

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