UDK: 547.857

Synthesis of novel potential antiviral agent – (rs)-9-[3-(2-benzoylphenoxy)-2-hydroxypropyl]adenine

A. A. Ozerov, M. S. Novikov, A. I. Luganchenko

Волгоградский медицинский научный центр, лаборатория медицинской химии

Abstract

The alkylation of adenine with 1-(2-benzoylphenoxy)-2,3-epoxypropane in anhydrous DMF in the presence of potassium carbonate leads to novel potential antiviral agent – (RS)-9-[3-(2-behzoylphenoxy)-2-hydroxypropyl]adenine with a yield of 29 %.

Keywords

adenine, epoxide, N-alkylation, antiviral agent

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