Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 547.854

Alkylation of 6-methyluracil with toluolsulfonate of 2(2-naphthyloxy) ethanol

A. I. Luganchgenko, V. S. Novikov, A. A. Ozerov

Волгоградский медицинский научный центр, лаборатория медицинской химии

Abstract

1-[2-(2-Naphthyloxy)ethyl]-6-methyluracil and 1,3-di[2-(2-naphthyloxy)ethyl]-6-methyluracil were synthesized with yields of 19 % and 54 % by alkylation of 6-methyluracil potassium salt with p-toluenesulfonate of 2-(2-naphthyloxy)ethanol in dimethylsulfoxide solution.

Keywords

6-methyluracil, toluenesulfonate, alkylation

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