UDK: 616-005.4

Morphometric study of the right hemisphere hyppocampus in rats in modeled hypertensive encephalopathy

A. V. Smirnov, M. V. Schmidt, D. S. Mednikov, M. R. Ekova, I. N. Tyurenkov, D. A. Bakulin

Волгоградский государственный медицинский университет, кафедра патологической анатомии, кафедра фармакологии и биофармации ФУВ; Волгоградский медицинский научный центр, лаборатория морфологии, иммуногистохимии и канцерогенеза

Abstract

The results of qualitative and quantitative studies of hippocampal pyramidal layer of the right hemisphere of rats in mod- elled hypertensive encephalopathy were presented. We revealed a reduction in the specific area of perikaryon in CA1, CA2, and CA3, an increase in the specific number of damaged neurons in all areas, as well as a decrease in the aver- age area of perikaryonic neurons in the areas CA1 and CA3, which demonstrated that the processes of reversible and irreversible damage occurred in modelled hypertensive encephalopathy.

Keywords

hippocampus, rat, hypertensive encephalopathy

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