UDK: 616.71-008.1:616.71-003.93

An experimental study of the use of intraarticular platelet-rich autoplasma therapy in rats with knee osteoarthritis

S. A. Demkin, D. A. Malanin, L. N. Rogova, G. L. Snigur, N. V. Grigorieva, K. V. Baidova

Волгоградский государственный медицинский университет, кафедра травматологии, ортопедии и ВПХ с курсом травматологии и ортопедии ФУВ; ГБУ «Волгоградский медицинский научный центр»

Abstract

We evaluated the morphological changes in the knee hyaline cartilage in 30 Wistar mature rats with experimental knee osteo- arthritis after intraarticular platelet-rich autoplasma therapy. Knee osteoarthritis has been shown to involve damage and destruction of the articular cartilage associated with vascular proliferation and granulomatous inflammation. The use of intraarticular platelet-rich autoplasma therapy resulted in a reduction of degenerative and dystrophic changes in the cartilage, an improvement of the tinctorial properties of the articular matrix.

Keywords

osteoarthritis, articular cartilage, platelet-rich autoplasma

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