UDK: УДК 651:547.466.3

ANALYTICAL FEATURES OF CHROMATOGRAPHIC METHOD OF QUANTITATIVE DETERMINATION OF GABA DERIVATIVES

L. A. Smirnova, I. N. Turenkov, V. N. Perfilova, A. F. Riabuha, E. A. Suchkov

Волгоградский государственный медицинский университет, лаборатория фармакокинетики НИИ фармакологии, кафедра фармакологии и биофармации ФУВ, лаборатория фармакологии сердечно-сосудистых средств НИИ фармакологии, ГУ ВМНЦ

Abstract

Analysis of current chromatographic methods of quantitative determination of GABA derivatives in biological samples was studied. Conditions of chromatographic analysis and extraction from biological samples providing optimal validation parameters were developed.

Keywords

HPLC, quantitative determination, GABA derivatives.

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