UDK: УДК 615:547.466

DERIVATIZATION AGENTS USED IN HPLC METHOD OF HOMOCYSTEIN DETERMINATION

A. F. Riabuha, L. A. Smirnova, K. A. Kuznetsov, E. A. Suchkov, V. N. Perfilova

Волгоградский государственный медицинский университет, лаборатория фармакокинетики НИИ фармакологии, кафедра фармакологии и биофармации ФУВ, ГУ ВМНЦ

Abstract

Analysis of different methods of homocystein determination in the plasma was performed. Two methods of determination were reproduced – HPLC methods of quantitative determination after derivatization with SBD-F and orthophtalic aldehyde.

Keywords

homocystein, HPLC, derivatization, OPA/2ME, SBD-F.

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