UDK: УДК 615:547.466.3

DEVELOPMENT OF METHOD OF QUANTITATIVE DETERMINATION OF NEW GABA DERIVATES IN BIOLOGICAL SAMPLES

L. A. Smirnova, A. F. Riabuha, K. A. Kuznetsov, E. A. Suchkov, V. N. Perfilova

НИИ фармакологии ВолгГМУ, ГУ ВМНЦ

Abstract

An analysis of current chromatographic methods of determination of GABA derivates in biological samples was performed.We determined the specific conditions of chromatographic analysis and extraction from biological samples providing optimum validation parameters.

Keywords

HPLC, quantitative determination, GABA derivates.

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