UDK: УДК 651:547.785.5

ANALYTICAL FEATURES OF CHROMATOGRAPHIC METHOD OF QUANTITATIVE DETERMINATION OF BENZIMIDAZOLE DERIVATIVES

L. A. Smirnova, A. A. Spasov, A. I. Raschenko, E. A. Suchkov, A. F. Riabuha, K. A. Kuznetsov

Лаборатория фармакокинетики НИИ фармакологии ВолгГМУ, кафедра фармакологии ВолгГМУ, ГУ ВМНЦ

Abstract

An analysis of current chromatographic methods of quantitative determination of benzimidazole of and imidazobenzimidazole derivatives in biological samples was performed. We determined the specific conditions of chromatographic analysis and extraction from biological samples providing optimum validation parameters.

Keywords

HPLC, quantitative determination, benzimidazoles, imidazobenzimidazoles.

Contacts