UDK: УДК 615.322:547.586.2
I. Yu. Mitrofanova, A. V. Yanitskaya
Волгоградский государственный медицинский университет, кафедра фармакогнозии и ботаники
We performed quantification of cinnamic acid in Inula britannica L. herb and studied the seasonal dynamics of its accumulation depending on the vegetative stage. The maximum cinnamic acid content in Inula britannica L. herb was found in the period of flowering of (5,04 ± 0,01) % and fruiting of (5,16 ± 0,01) %. The single measurement error was 0,76 and 0,70%, respectively. Thus, the optimum period for preparation of Inula britannica L. herb in accordance with the cinnamic acid maximum accumulation is the periods of flowering and fruiting. In addition, we have made a validation assessment of the cinnamic acid quantification technique. It was established that all the values of proxy indicators are within the acceptable limits, the technique was valid for indices of specificity, linearity and analytical region techniques, accuracy and reproducibility; it can be used for cinnamic acid quantification in the studied raw materials — Inula britannica L. herb.
Inula britannica L., cinnamic acid, spectrophotometry