Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 616.12-008.46-039:616.24

Clinical peculiarities, life quality and cardio-renal relationships in patients with chronic heart failure and chronic obstructive pulmonarydisease

Волгоградский государственный медицинский университет, Волгоградская городская клиническая больница № 3

Abstract

134 patients with CHF and CHF with concomitant COPD were examined. Clinical supervision was car ried out for all patients, CHF FC was determined, echocardiography was performed, functional renal status and ext ernal respiratory function were examined, and life quality was assessed. Arterial hypertension and supraventricular an d ventricular heart rhythm disturbance were observed more often in patients with CHF accompanied by COPD though CHF FC was the same. So life quality is reliably reduced judging by the results of Minnesotan questionnaire. Th ere was an increased left ventricular diastolic dysfunction, unfavorable types of remodeling of the left ventricle, progr ession of pulmonary hypertension among patients with CHF accompanied by COPD in comparison with patients with CHF. Among the patients with CHF accompanied by COPD in comparison with patients with CHF we discovered more often a clinically significant decrease of the glomerular filtration rate (<60 ml/min/1,73 m2), exhausted functional renal reserve and higher albumin renal excretion. Besides, significant cardio-renal relationships were determined in patients with CHF accompanied by COPD. The revealed features of clinical presentations and target organs lesion aggrav ate the course of disease and require strict control of administered treatment in patients with CHF accompanied by COPD.

Keywords

chronic heart failure, chronic obstructive pulmonary disease, life quality, cardio-renal relationship

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