UDK: 615.281.8:547.854.4

Predicting the toxicity and metabolism of 1-[2-(4-methylbenzyloxy)ethoxymethyl]-5-bromo-6-methyluracil with anti-hiv-1 activity in vitro

Yu. A. Orlova, M. S. Novikov, A. A. Ozerov

Волгоградский государственный медицинский университет, кафедра фармацевтической и токсикологической химии

Abstract

Biological activity, toxicity and metabolism of 1-[2-(4-methylbenzyloxy)-ethoxymethyl]-5-bromo-6-methyluracil have been studied by in silico methods.

Keywords

anti-HIV-1 activity, prediction, toxicity, metabolism

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