Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 615.3:616-073

Assay of compound RU-1205 in biological samples

L. A. Smirnova, A. I. Raschenko, A. F. Riabuha, K. A. Kuznecov, E. A. Suchkov

Волгоградский государственный медицинский университет, кафедра фармакологии, лаборатория фармакокинетики НИИ фармакологии ВолгГМУ


We developed a method for chromatographic assay of a new biologically active compound, a benzimidazole derivative, RU-1205 using high performance liquid chromatography (HPLC). Sensitivity, time of substance retention, maximal absorption of the compound in the UV spectrum were determined. We also performed a selection of an extracting agent from biological samples.


HPLC, assay, benzimidazole