UDK: 616.91-092.9:616.24

WNV antigen expression in the lungs of mice in experimental modeling of West Nile fever

A. V. Smirnov, A. M. Butenko, G. L. Snigur, L. S. Bykhalov, N. V. Khutoretskaya, V. F. Larichev

Волгоградский государственный медицинский университет, Волгоградский медицинский научный центр

Abstract

An immunohistochemical study using monoclonal antibodies to West Nile virus showed nuclear and cytoplasmic expression of antigens, which was most pronounced in alveolar macrophages and the endothelium of blood capillaries in the pulmonary interalveolar septa group of animals with clinical signs of West Nile fever on the 7th day from the moment of infection.

Keywords

monoclonal antibodies, alveolar macrophages, antigen, fever

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