UDK: 615.3:547.854.4

Antiviral agents. VI. Synthesis of new 1-cinnamyl-3-benzyluracil derivatives

M. P. Paramonova, D. A. Babkov, A. A. Ozerov, M. S. Novikov, G. N. Solodunova

Кафедра фармацевтической и токсикологической химии ВолгГМУ, Лаборатория фармацевтической химии Волгоградского медицинского научного центра

Abstract

Treatment of 1-cinnamiluracil with benzylhalides containing different substituents in aromatic cycle led to 3-benzyl-1-cinnamyluracil derivatives with a 73—81 % yield. These compounds are of interest as potential anti-HIV-1 agents.

Keywords

ynthesis, uracil, N-alkylation, potential antiviral agents

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