Volgograd Journal of Medical Research
Quarterly Journal of Science and Practice

UDK: 616-091.9:616.4

Morphological changes in the organs of the immune system of rats in experimental model of magnesium deficiency

A. V. Smirnov, M. V. Schmidt, N. G. Panshin, O. U. Yevsyukov, A. M. Yevtushenko

Кафедра патологической анатомии ВолгГМУ, Волгоградский медицинский научный центр


Morphological changes in the immune organs of rats in a model of magnesium deficiency indicate a decrease in the lymphocyte population. Reduction or complete disappearance of germinal centers in lymphoid follicles of the spleen and a decrease in the number of lymphocytes in the medulla of lymph nodes may be indirect evidence of reduction in the number of plasma cells producing immunoglobulins.


magnesium deficiency, thymus, spleen, lymph node