UDK: 616-006:616-006.3.04

Algorithm of immunohistochemical biomarkers expression prognostic significance evaluation in morphological diagnosis of Ewing’s sarcoma family tumors

Bulanov D. V., Smirnov A. V., Zagrebin V. L., Gurov D. Yu.

Московская городская онкологическая больница № 62, кафедра патологической анатомии, кафедра гистологии, эмбриологии, цитологии ВолгГМУ, Волгоградский медицинский научный центр

Abstract

An algorithm for the evaluation of the prognostic value of immunohistochemical expression of biomarkers of Ewing’s sarcoma family tumors is proposed. It is shown that immunohistochemical tumor characteristics determine morphological heterogeneity and are significant predictors.

Keywords

Ewing’s sarcoma family of tumors, proliferation markers, apoptosis, immunohistochemical characteristics

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